Treatment

For Hypokalemic Periodic Paralysis:

Effer-K

Effer-K® is an effervescent liquid prescription potassium supplement in tablet form. Simply drop the tablet into a glass of water, wait one minute for the tablet to dissolve, then enjoy the non-carbonated beverage.

Effer-K® is the combination of potassium bicarbonate and citric acid as an effervescent tablet. When placed in water, or other aqueous liquids, the citric acid and potassium bicarbonate react. The effervescent reaction provides potassium as potassium citrate in a slightly acidic solution. The initial bicarbonate molecule is bubbled off as carbon dioxide and water. Potassium citrate and water remain. Potassium citrate is the type of potassium found naturally in fruit, which is why Effer-K® does not have the harsh, salty taste associated with other forms of potassium.

 

  

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Potasium Chloride Solution

Potassium is a mineral that is found in many foods and is needed for several functions of your body, especially the beating of your heart.

Potassium chloride is used to prevent or to treat low blood levels of potassium (hypokalemia).

Potassium levels can be low as a result of a disease or from taking certain medicines, or after a prolonged illness with diarrhea or vomiting.

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Dichlorphenamide

KEVYIS (pronounced keh-VAY-iss) (dichlorphenamide) is a prescription drug used to treat primary hyperkalemic periodic paralysis, primary hypokalemic periodic paralysis, and other similar diseases.

Brand:

Keveyis (formerly Daranide) by Strongbridge Biopharma TM


Mechanism of Action
:

carbonic anhydrase inhibitor

 

Commentary:

See the following url for availability at Strongbridge TM CareConnection

Patient Assistance telephone: 844-KEVEYIS (844-538-3947)

 

For additional information on Keveyis, go to the Keveyis website


Eplerenone

Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.

High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

  

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Spironolactone

Spironolactone is a potassium-sparing diuretic (water pill) that prevents your body from absorbing too much salt and keeps your potassium levels from getting too low.

Spironolactone is used to treat heart failurehigh blood pressure (hypertension), or hypokalemia (low potassium levels in the blood).

 

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Triamterene

Triamterene is a potassium-sparing diuretic (water pill) that prevents your body from absorbing too much salt and keeps your potassium levels from getting too low.

Triamterene is used to treat fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney condition called nephrotic syndrome.

Triamterene is also used to treat edema caused by using steroid medicine or having too much aldosterone in your body. Aldosterone is a hormone produced by the adrenal glands to help regulate the salt and water balance in your body.

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Amiloride

It is used to treat or prevent low potassium levels.

 

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For Hyperkalemic Periodic Paralysis:

Acetazolamide

It is used to get rid of extra fluid.
It is used to treat or prevent altitude sickness.
It is used to help control certain kinds of seizures.
It is used to treat glaucoma.
It may be given to you for other reasons.

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Dichlorphenamide

KEVYIS (pronounced keh-VAY-iss) (dichlorphenamide) is a prescription drug used to treat primary hyperkalemic periodic paralysis, primary hypokalemic periodic paralysis, and other similar diseases.

Brand:

Keveyis (formerly Daranide) by Strongbridge Biopharma TM


Mechanism of Action
:

carbonic anhydrase inhibitor

 

Commentary:

See the following url for availability at Strongbridge TM CareConnection

Patient Assistance telephone: 844-KEVEYIS (844-538-3947)

 

For additional information on Keveyis, go to the Keveyis website


Acute Attacks

Simple carbohydrates

Albuterol

Lowers the potassium.

Albuterol (also known as salbutamol) is used to prevent and treat wheezing and shortness of breath caused by breathing problems (such as asthma, chronic obstructive pulmonary disease). It is also used to prevent asthma brought on by exercise. It is a quick-relief medication. Albuterol belongs to a class of drugs known as bronchodilators. It works in the airways by opening breathing passages and relaxing muscles.

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